Programme

The program schedule is still being finalized and will be updated over time.


13th October 2025 (Day 1)
12pm Registration and light lunch
2pm Opening address by Organizing Committee
Session: Advances in HCV, flaviviruses and other viruses
2.15pm Keynote Speaker: Prof. Dan Barouch
Correlates of Protection for Respiratory Virus Vaccines
3.15pm Afternoon Break
3.30pm Oral presentations

High resolution structural analysis of an HCV E1E2 ectodomain complex
Presented by: A/Prof. Gilad Ofek

A novel computational approach to define epitopes of HCV neutralizing antibodies
Presented by: Mr. Harry Paul

G-quadruplexes in Dengue virus 3' UTR regulate the viral replication cycle
Presented by: Prof. Trushar Patel

Host Genetic Determinants of Flavivirus Infection in Mammalian and Vector Systems
Presented by: Dr. Hans-Heinrich Hoffmann

TBA
5pm Poster short talks/Rapid fire talks 1

Genome-wide CRISPR screen identifies EIF4H and YBX1 as essential host factors for HEV replication
Presented by: Dr. Qiang Ding

Blood-Brain Barrier Disruption and NS1-Mediated Pathogenesis in Tick-Borne Encephalitis Virus Infection
Presented by: Dr. Martin Palus

Dynamic Profiling of Flaviviral Infection and Replication Dynamics with Host Responses Using Real-Time Bioluminescence
Presented by: A/Prof. Masahiko Ito

Synthesis and biochemical evaluation of non-structural polyprotein of Flaviviridae using a wheat cell-free system with nanodisc technology
Presented by: A/Prof. Hirotaka Takahashi

AlphaFold3-Enabled Discovery of Early Infection Antibody Targets in an HCV Super Clearer
Presented by: Dr. Ahmed Abdul Quadeer

Roles of rodent orthologues of HCV entry factors in NRHV1 infection
Presented by: A/Prof. Tomohisa Tanaka

Between- and within-host mutation of dengue virus
Presented by: Mr. Sachith Wijethunga Arachchige

5.30pm Welcome Reception
End of Day 1
14th October 2025 (Day 2)
Session: Public health/Clinical Science and Epidemiology of Hepatitis C and Flaviviruses
Session Chair: Dr. Michael Diamond
9am Plenary: Prof. Eva Harris
Immune imprinting of dengue and Zika viruses: Immunological, epidemiological, and clinical consequences
9.30am Oral presentations

Unravelling Ribavirin's Mechanism: In Vivo Insights from STOPHCV-1 Clinical Trial
Presented by: Dr. Mahdi Moradi Marjaneh

Development of a novel model of HCV transmission that accounts for ongoing viral evolution
Presented by: Dr. Bethany Horsburgh

Dengue virus infection reprograms baseline innate immune gene expression
Presented by: Dr. Eugenia Ong

Silencing of key non-neutralizing epitopes of the HCV E2 glycoprotein to refocus the immune response.
Presented by: Prof. Heidi Drummer

More talks to be announced
10.30am Morning tea
11am Plenary: Dr. Marianne Martinello
Towards HCV elimination in Australia
11.30am TBA
12pm Lunch
Session: Virus Life Cycle
Session Chair: Prof. Jason Mackenzie
1pm Plenary: Prof. Jens Bukh
Hepaci-Flavi Lifecycle: In Vitro and In Vivo Experimental Systems and Antivirals
1.30pm Oral presentations

Fats, FASN and Flaviviruses: functional dependency and immune competency in macrophages
Presented by: Prof. Jason Mackenzie

LRP8 is a receptor for tick-borne encephalitis virus
Presented by: Dr. Eva Mittler

An integrated proteomic approach identifies a conserved and non-canonical role for UFMylation in orthoflavivirus replication
Presented by: Dr. Sreejith Rajasekharan

Nur77 Modulates HCV Replication Through Interaction with NS5B RNA polymerase
Presented by: Prof. Ju-Chien Cheng
2.30pm Afternoon break
3.30pm Poster short talks/Rapid fire talks 2

Studies on DAAs efficacy among different HCV-infected patient groups and RAS analysis against HCV GT3 and 1c non-responder patients in tertiary care hospitals in West Bengal, India
Presented by: Mr. Sagnik Bakshi

Profiling HCV vaccine-induced antibody responses with E2 epitope knockout (Eko) probes
Presented by: Dr. Xander Wilcox

Unraveling HCV Diversity and Resistance in Vietnam: Implications for Treatment
Presented by: Ms. Chau Le Ngoc

The interferon and interferon-stimulated gene response of the first trimester placenta to Zika virus infection.
Presented by: Dr. Kylie Van der Hoek

Development of an immunogenic single-dose live attenuated ZIKV vaccine using an orthoflavivirus genome recoding platform
Presented by: Dr. Chin Wen Xin

Lost in translation: Flavivirus infection and the production of tRNA halves
Presented by: Dr. Rhys Parry

Evaluating Usutu virus infection dynamics and potential therapeutics using a fluorescent reporter
Presented by: Ms. Amy Nelson

Specialized RNA Secondary Structures of Avian Flavivirus 3'UTR Regulate Viral Avian Host shifting
Presented by: Prof. Shun Chen
4pm Poster Session 1
6pm Closing announcements & end of Day 2
15th October 2025 (Day 3)
Session: Vaccines and therapeutics
Session Chairs: Dr. Jody Peters, A/Prof. Branka Grubor-Bauk
9am Plenary: Prof. Sudhanshu Vrati
Role of the host proteins in Japanese encephalitis virus replication
9.30am Oral presentations

Comparisons of ChAdOx viral vector and mRNA-LNP vaccines encoding HCV sE2 or E1E2 from an antigenic HCV clade selected to induce broadly neutralising antibody responses
Presented by: Dr. Matthew Edmans

A Skin-Targeted Vaccine Patch Against Hepatitis C Virus
Presented by: Prof. Thomas Fuerst

Multi-Antigen DNA Vaccine Induces Potent T Cell Protection Against Zika Virus
Presented by: Mr. Ryan Santos

Imprinting of the host epigenome after Hepatitis C virus cure is affected by treatment regime
Presented by: A/Prof. Meital Gal Tanamy

10.30am Morning tea
11am Plenary: Prof. Andrea Cox
Natural Hepatitis C Virus Infection Informing Vaccine Design
11.30am Oral presentations

An mRNA vaccine with enhanced virus-like particle production promotes immune responses and clearance of Norway rat hepacivirus infection.
Presented by: Dr. Hae-Gwang Jung

ISVac Chimeric Vaccines: From Veterinary Efficacy to Advancements for Human Application
Presented by: Dr. Jody Peters

12pm Lunch
Session: Evolution, emergence and vectors
Session Chair: Prof. Marco Vignuzzi
1pm Plenary: Prof. Saravanan Thangamani
Emerging Powassan Virus Strains: Genetic and Phenotypic Insights into Transmission, Perpetuation, and Public Health Risk
1.30pm Oral presentations

Genomic phylogeny and protein structure analyses of 'flavi-like' viruses support a major taxonomic expansion and reorganization of the Flaviviridae
Presented by: Dr. Peter Simmonds

Longitudinal characterization of protective antibody responses and neutralization resistance in hepatitis C virus infection
Presented by: Ms. Suzanne van den Aardweg

A cholesterol binding domain within the dengue virus NS1 protein differentiates virus replication between mammalian and mosquito cells
Presented by: Dr. David Muller

Rat liver cells as a reverse zoonosis model to study hepatitis E virus cross-species transmission
Presented by: Dr. Nicola Frericks
2.30pm Afternoon break
3.30pm Poster Session 2
6pm Closing announcements & end of Day 3
16th October 2025 (Day 4)
Session: Pathogenesis
Session Chairs: Prof. Kartik Chandran, A/Prof. Sylvie Alonso
9am Plenary: Prof. Neelika Malavige
Pathogenesis of Severe Dengue in the Context of Obesity: Roles of T Cells, Monocytes, and Oxidative Stress
9.30am Oral presentations

Lentiviral vectors illuminate novel facets of orthoflavivirus entry and transmission
Presented by: A/Prof. Florian Douam

Building a complex understanding of dengue microvascular dysfunction through novel in vitro 3D multicellular systems
Presented by: Dr. Kevin Maringer

Powassan virus induces sex-specific neurological disease and long-lasting sequelae in C57BL/6Ntac mice.
Presented by: Dr. Devin Kenney

Developing a molecular recorder for dengue virus infection
Presented by: Mr. Marcus Curlee

10.30am Morning tea
11am Plenary: Prof. Thomas Baumert
Hepatitis C Virus and the Circadian Clock: Impact for Liver Disease Biology and Cancer Risk
11.30am Oral presentations

Platelet-secreted exosomal miRNAs enhance vascular dysfunction in dengue infection
Presented by: A/Prof. Shubham Shrivastava

Age-stratified immune responses reveal distinct mechanisms underlying dengue resolution and severe disease progression
Presented by: Dr. Veronica Duran
12pm Lunch
Session: Innate and Adaptive Immunity
Session Chairs: Prof. Alexander Ploss, Prof. Karla Helbig
1pm Plenary: Prof. Ellie Barnes
Vaccines for HCV – antigens and platforms in 2025
1.30pm Oral presentations

Immune profiling in subclinical secondary dengue-infected cases reveals adaptive immune signatures correlated to protection from severe dengue.
Presented by: Dr. Tineke Cantaert

A Rare HCV E2 Antibody That Defies the Classic Easy- and Hard-to-Neutralize Divide
Presented by: Mr. Filip Popovic

Fueling Immunity: Engineering Lipid Droplets to Combat Viral Infection Review
Presented by: Prof. Karla Helbig

Liver as a self-sustaining niche for locally generated plasma cells after hepatotropic viral infection
Presented by: Dr. John Gridley
Session: Structural Biology and Therapeutic Targets
Session Chairs: Prof. Richard Kuhn, A/Prof. Andrew Flyak
2.30pm Plenary: Prof. Sheemei Lok
Dengue virus NS1 dynamic structures
3pm Oral presentations

Structural studies of HCV pseudoparticles and cell surface antigen display
Presented by: Prof. Richard Kuhn

Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein (HDL)
Presented by: Prof. Dahai Luo

Immunogenicity and structural characterization of stabilized recombinant hepatitis C virus E1E2 immunogens
Presented by: Mr. Joan Capella Pujol

Elucidating the Conformational Flexibility and Shielding Properties of HVR1 on Hepatitis C Virus E1E2 Envelope Glycoprotein Complex a161
Presented by: Dr. Shr-Hau Hung

4pm Announcements, closing remarks
4.45pm Shuttle bus to Singapore Zoo
5.30pm-late Networking dinner